Monitoring oxygen delivery in critically ill newborns using advanced optical technology
Monitoring of Oxygen Delivery and Tissue Oxygenation Deprivation in Critically Ill Neonates Using Resonance Raman Spectroscopy
This study is testing a new, gentle way to check how much oxygen is getting to the tissues of very sick newborns, helping doctors spot problems early and provide better care.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pendar Technologies, LLC NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11007510 on NIH RePORTER |
What this research studies
This research focuses on developing a non-invasive optical probe that monitors tissue oxygen levels in critically ill neonates. By utilizing resonance Raman spectroscopy, the study aims to provide real-time assessments of oxygen delivery to tissues, which is crucial for identifying shock states in newborns. Traditional methods of measuring oxygen levels can be misleading, so this innovative approach seeks to improve the accuracy of monitoring and enhance patient care. The goal is to enable early detection of critical conditions, allowing for timely interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns aged 0-4 weeks who are critically ill and require close monitoring of their oxygen delivery.
Not a fit: Patients who are not critically ill or are older than 4 weeks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment of critically ill neonates, potentially reducing mortality rates.
How similar studies have performed: While the use of resonance Raman spectroscopy is a novel approach in this context, similar non-invasive monitoring techniques have shown promise in other critical care settings.
Where this research is happening
Cambridge, United States
- Pendar Technologies, LLC — Cambridge, United States (Active)
Researchers
- Principal investigator: Vakhshoori, Daryoosh — Pendar Technologies, LLC
- Study coordinator: Vakhshoori, Daryoosh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.