Monitoring oxygen delivery in critically ill newborns using advanced optical technology
Official title: Monitoring of Oxygen Delivery and Tissue Oxygenation Deprivation in Critically Ill Neonates Using Resonance Raman Spectroscopy
Funded at Pendar Technologies, LLC · NIH-11007510 · Data updated 2026-11-12
This study is testing a new, gentle way to check how much oxygen is getting to the tissues of very sick newborns, helping doctors spot problems early and provide better care.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pendar Technologies, LLC NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $318,724 |
| NIH project number | 1R43HD116647-01 |
| Project ID | NIH-11007510 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are newborns aged 0-4 weeks who are critically ill and require close monitoring of their oxygen delivery.
✕Less likely to help
Patients who are not critically ill or are older than 4 weeks may not benefit from this research.
What this research studies
This research focuses on developing a non-invasive optical probe that monitors tissue oxygen levels in critically ill neonates. By utilizing resonance Raman spectroscopy, the study aims to provide real-time assessments of oxygen delivery to tissues, which is crucial for identifying shock states in newborns. Traditional methods of measuring oxygen levels can be misleading, so this innovative approach seeks to improve the accuracy of monitoring and enhance patient care. The goal is to enable early detection of critical conditions, allowing for timely interventions.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment of critically ill neonates, potentially reducing mortality rates.
How similar studies have gone: While the use of resonance Raman spectroscopy is a novel approach in this context, similar non-invasive monitoring techniques have shown promise in other critical care settings.
Where this research is happening
-
Pendar Technologies, LLC
Cambridge, United States Active
Researchers
- Principal investigator: Vakhshoori, Daryoosh — Pendar Technologies, LLC
- Study coordinator: Vakhshoori, Daryoosh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.