Monitoring liver health through a blood test for antioxidants
Noninvasive Monitoring of Hepatic Glutathione Depletion Through Blood Test
This study is working on a simple blood test to check your glutathione levels, which can help spot early signs of liver damage and other health issues related to stress in the body, making it easier for you to keep track of your liver health without needing any invasive procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Dallas NIH-funded |
| Lab location | 1 site (Richardson, United States) |
| Project ID | NIH-10771108 on NIH RePORTER |
What this research studies
This research focuses on developing a noninvasive blood test to monitor levels of glutathione, a key antioxidant produced in the liver. By measuring glutathione depletion, the research aims to identify early signs of liver damage and other diseases linked to oxidative stress, such as Parkinson's disease and immunodeficiency. The approach seeks to overcome the limitations of current methods that require invasive procedures or expensive imaging techniques. Patients will benefit from a simple blood test that could provide critical information about their liver health and overall oxidative stress levels.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for liver diseases or those experiencing symptoms related to oxidative stress.
Not a fit: Patients with stable liver function and no risk factors for oxidative stress-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable earlier detection and management of liver-related diseases and other conditions associated with oxidative stress.
How similar studies have performed: While there have been advances in monitoring oxidative stress, this specific noninvasive approach using blood tests for glutathione levels is novel and has not been widely tested.
Where this research is happening
Richardson, United States
- University of Texas Dallas — Richardson, United States (Active)
Researchers
- Principal investigator: Zheng, Jie — University of Texas Dallas
- Study coordinator: Zheng, Jie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.