Monitoring how stress affects adolescents at risk for psychosis
Ambulatory Monitoring of Threat Dysregulation in Adolescents at Risk for Psychosis
['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10836348
This study is looking at how stress affects social interactions and experiences of psychosis in teenagers aged 12 to 20, to help us understand how their bodies respond to stress and how that might impact their daily lives over the course of a year.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10836348 on ClinicalTrials.gov |
What this research studies
This research investigates how physiological responses to stress, known as threat dysregulation, impact social interactions and experiences of psychosis in adolescents aged 12 to 20. By using various methods such as laboratory assessments and real-time monitoring of physiological responses, the study aims to understand the relationship between stress responses and social impairment over a year. The research focuses on the role of the body's stress systems, including the HPA axis and autonomic nervous system, in contributing to these challenges during a critical developmental period.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are identified as being at risk for psychosis.
Not a fit: Patients who are outside the age range of 12 to 20 or those who do not exhibit risk factors for psychosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and interventions for adolescents at risk of developing psychosis, improving their social functioning and overall mental health.
How similar studies have performed: Previous research has shown that monitoring physiological responses to stress can provide valuable insights into mental health conditions, suggesting that this approach may yield meaningful results.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HORTON, LESLIE E — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: HORTON, LESLIE E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.