Monitoring heart and blood pressure changes in animals exposed to toxic chemicals
Evaluation of Physiological Monitoring in Toxicology using 2-Ethyltoluene as a case study
This study is looking at how tracking heart rate and blood pressure in animals can help us spot early signs of harm from toxic chemicals, which could lead to better ways to monitor and protect people from similar dangers.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Centers/pub Hlth Res & Evaluatn NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-11216082 on NIH RePORTER |
What this research studies
This research evaluates how physiological monitoring, such as heart rate and blood pressure, can be used to assess the effects of toxic chemicals on animals. By implanting telemetry devices, researchers will track these vital signs in real-time during exposure to harmful substances. The goal is to identify early signs of toxicity before severe health issues arise, potentially allowing for timely interventions. The findings could translate to better health monitoring practices for humans exposed to similar toxins.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals involved in toxicology studies or those exposed to environmental toxins.
Not a fit: Patients who are not exposed to toxic chemicals or do not participate in toxicology assessments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection of toxic effects in both animals and humans, enhancing safety protocols.
How similar studies have performed: Previous research has shown that physiological monitoring can effectively indicate health changes in response to toxic exposures, supporting the potential success of this approach.
Where this research is happening
Columbus, United States
- Battelle Centers/pub Hlth Res & Evaluatn — Columbus, United States (Active)
Researchers
- Principal investigator: Fallacara, Dawn — Battelle Centers/pub Hlth Res & Evaluatn
- Study coordinator: Fallacara, Dawn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.