Monitoring fluid levels in heart failure patients using a non-invasive device
Official title: Non-Invasive Venous waveform Analysis (NIVA) for Monitoring Volume Status in Heart Failure Patients
Funded at Vanderbilt University Medical Center · NIH-10981403 · Data updated 2026-11-12
This study is working on a special device that helps monitor fluid levels in people with heart failure, especially those with certain heart conditions or who have had heart transplants, to make sure they get the best care possible.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | August 1, 2019 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $392,932 |
| NIH project number | 2R01HL148244-06 |
| Project ID | NIH-10981403 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include heart failure patients, particularly those with tricuspid regurgitation, heart transplant recipients, and individuals supported by left ventricular assist devices.
✕Less likely to help
Patients without heart failure or those not experiencing complications related to fluid volume status may not benefit from this research.
What this research studies
This research focuses on enhancing a non-invasive device called the Non-Invasive Venous waveform Analysis for Heart Failure (NIVAHF), which monitors fluid levels in heart failure patients. The device uses advanced AI algorithms to analyze venous waveforms and generate a score that reflects the patient's volume status, crucial for managing heart failure. The study aims to address challenges faced by patients with tricuspid regurgitation, those who have had heart transplants, and patients with left ventricular assist devices. By improving this technology, the research seeks to provide more accurate and timely monitoring for these vulnerable populations.
Why it matters
Potential benefit: If successful, this research could lead to better management of heart failure, reducing complications and improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using non-invasive monitoring techniques in cardiology, indicating potential for success with this novel approach.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Alvis, Bret D — Vanderbilt University Medical Center
- Study coordinator: Alvis, Bret D
Related research
Other NIH-funded projects on the same topics.
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Non-Invasive Venous Waveform Analysis for Heart Failure Monitoring
A new non-invasive device uses AI to monitor fluid status in people with heart failure to help guide care.
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Non-invasive venous waveform monitor for fluid status in heart failure patients
This project uses a small sensor and AI to estimate vein pressure so people with heart failure can get easier, non-invasive monitoring of their fluid status.
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Lowering heart failure risk for people with diabetes and low income
This project brings problem-solving training, community health workers, and local support to people with diabetes, obesity, and low income who have early heart changes to help improve fitness, control risk factors, and feel better.
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Exploring how low socioeconomic status and diabetes affect heart failure risk
This study is looking at how being low-income and having diabetes can affect your heart health, especially for people from different racial and ethnic backgrounds, and it will involve 350 participants trying out helpful programs to improve their health and lifestyle.
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Impact of the DASH diet on heart failure in older adults
This study is looking at how a special diet called the DASH diet can help improve heart health in older adults over 65 with heart failure, by providing them with meals delivered to their homes and checking how it affects their health.
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AI-supported heart failure diagnosis and management in Rwanda
Aiming to help people with suspected heart failure in Rwanda get faster, more accurate diagnoses and better care using AI-guided ultrasound and care protocols.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.