Monitoring common respiratory and stomach viruses in children

IP21-002, Enhanced Surveillance Network for Enteric and Respiratory Viruses in Children: Assessing Disease Burden, Natural History, and Vaccine Effectiveness

NIH-funded research University of Rochester · NIH-11138404

We track breathing and stomach viruses in children to learn how often they make kids sick and how well vaccines keep them out of the hospital.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11138404 on NIH RePORTER

What this research studies

This project strengthens a long-running network that enrolls children who come to hospitals and clinics with respiratory or gastrointestinal symptoms and collects clinical data and laboratory samples. Study teams take nasal swabs or stool samples, check for viruses in the lab, and record vaccination history and clinical outcomes. Those data are used to measure how often specific viruses cause hospital visits and to estimate how well vaccines prevent serious illness. The network can also quickly switch to study new threats like enterovirus D68 or SARS-CoV-2 and related syndromes such as AFM and MIS-C.

Who could benefit from this research

Good fit: Children who seek care or are hospitalized for cough, difficulty breathing, fever, vomiting, or diarrhea at participating hospitals or clinics are the ideal candidates.

Not a fit: Children without respiratory or gastrointestinal symptoms, or those who do not live near participating sites, are unlikely to be eligible or see direct benefit.

Why it matters

Potential benefit: Results could help doctors and public health officials use vaccines and treatments more effectively to prevent hospital visits for children with viral infections.

How similar studies have performed: Prior NVSN and other surveillance efforts have successfully measured disease burden and guided vaccine policy for influenza, rotavirus, and RSV.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.