Monitoring brain changes during reading lessons in children with and without reading difficulties

Tracking neurocognitive changes during evidence-based reading instruction in typically and atypically developing children

NIH-funded research University of Connecticut Storrs · NIH-11174319

Researchers will follow brain activity and learning during evidence-based reading lessons in young children with and without reading difficulties to find what helps some kids improve and why others do not.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project IDNIH-11174319 on NIH RePORTER

What this research studies

If your child takes part, they would get brain imaging before learning and regular, shorter brain monitoring sessions during a course of reading lessons, plus a final scan afterward. The team uses MRI and MRS for detailed pre-learning brain measures and portable fNIRS and EEG to track brain function frequently during the intervention. Children who respond well and those who make only small gains will be compared to identify different learning patterns. Findings will be used to try short-term adaptive lessons aimed at children who do not improve with standard instruction.

Who could benefit from this research

Good fit: Young children in early school years who are struggling with reading or have a diagnosed reading disability, and typically developing children willing to serve as comparison participants.

Not a fit: Adults, children outside the study age range, or children with unrelated severe medical or neurological conditions are unlikely to be eligible or see direct benefit from this project.

Why it matters

Potential benefit: Could lead to more personalized reading programs that help children who currently do not improve with standard reading instruction.

How similar studies have performed: Prior work, including the team's earlier project, has shown brain changes after reading remediation and identified predictors of who improves, but continuous brain tracking and adaptive targeting of non-responders are more novel.

Where this research is happening

Storrs-Mansfield, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.