Monitoring brain activity and health in patients with severe brain injuries

Intracranial multimodal physiological monitoring in acute brain injury

NIH-funded research Yale University · NIH-11067148

This study is testing a new device called the NeuroProbe that will help doctors keep a closer eye on patients with serious brain injuries by combining several monitoring tools into one, making it easier and safer for you during treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11067148 on NIH RePORTER

What this research studies

This research aims to improve the monitoring of patients with acute brain injuries by developing a new device that combines multiple monitoring functions into one implantable solution. Currently, monitoring requires several invasive probes, which can be cumbersome and risky. The new device, called the NeuroProbe, will measure critical parameters like intracranial pressure and brain tissue oxygen, while the NeuroLink will collect and integrate this data with other physiological information. This streamlined approach could enhance patient care and outcomes in severe traumatic brain injury cases.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from acute traumatic brain injuries, particularly those requiring intensive monitoring.

Not a fit: Patients with mild brain injuries or those who do not require invasive monitoring may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective monitoring of brain health in patients with severe brain injuries.

How similar studies have performed: Previous research has shown promise in multimodal monitoring approaches for brain injuries, indicating potential for success with this integrated device.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.