Monitoring blood flow in the brain during stroke treatment

Noninvasive monitoring of cerebrovascular autoregulation during and after endovascular therapy for acute ischemic stroke

NIH-funded research University of South Florida · NIH-10771295

This study is testing a new, noninvasive way to check blood flow in the brain during and after treatment for strokes, using a special tool that helps doctors catch any problems early and improve care for patients.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of South Florida NIH-funded
Lab location1 site (Tampa, United States)
Project IDNIH-10771295 on NIH RePORTER

What this research studies

This research focuses on improving the management of acute ischemic strokes by developing a noninvasive method to monitor cerebral blood flow during and after endovascular therapy. Using a new optical instrument called Diffuse Correlation Spectroscopy (DCS), the study aims to provide real-time, accurate measurements of blood flow in the brain's microvasculature. This approach seeks to enhance treatment personalization and optimize patient outcomes by identifying potential complications early. The goal is to address the current limitations in monitoring techniques that often delay necessary interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients experiencing acute ischemic strokes due to large vessel occlusion.

Not a fit: Patients with strokes not caused by large vessel occlusion or those who are not undergoing endovascular therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better management of stroke patients, reducing the risk of complications and improving recovery outcomes.

How similar studies have performed: While the use of noninvasive monitoring techniques is gaining traction, this specific approach using DCS for real-time blood flow measurement in stroke therapy is relatively novel.

Where this research is happening

Tampa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.