Monitoring blood flow in the brain during stroke treatment
Official title: Noninvasive monitoring of cerebrovascular autoregulation during and after endovascular therapy for acute ischemic stroke
Funded at University of South Florida · NIH-10771295 · Data updated 2026-11-12
This study is testing a new, noninvasive way to check blood flow in the brain during and after treatment for strokes, using a special tool that helps doctors catch any problems early and improve care for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $183,621 |
| NIH project number | 5R21NS130495-02 |
| Project ID | NIH-10771295 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients experiencing acute ischemic strokes due to large vessel occlusion.
✕Less likely to help
Patients with strokes not caused by large vessel occlusion or those who are not undergoing endovascular therapy may not benefit from this research.
What this research studies
This research focuses on improving the management of acute ischemic strokes by developing a noninvasive method to monitor cerebral blood flow during and after endovascular therapy. Using a new optical instrument called Diffuse Correlation Spectroscopy (DCS), the study aims to provide real-time, accurate measurements of blood flow in the brain's microvasculature. This approach seeks to enhance treatment personalization and optimize patient outcomes by identifying potential complications early. The goal is to address the current limitations in monitoring techniques that often delay necessary interventions.
Why it matters
Potential benefit: If successful, this research could lead to better management of stroke patients, reducing the risk of complications and improving recovery outcomes.
How similar studies have gone: While the use of noninvasive monitoring techniques is gaining traction, this specific approach using DCS for real-time blood flow measurement in stroke therapy is relatively novel.
Where this research is happening
-
University of South Florida
Tampa, United States Active
Researchers
- Principal investigator: Parthasarathy, Ashwin Bharadwaj — University of South Florida
- Study coordinator: Parthasarathy, Ashwin Bharadwaj
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Aims to develop quick MRI techniques to identify tissue at risk in acute ischemic stroke and help decide whether to use advanced clot-busting treatment.
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This grant looks at how the body’s internal clock might influence how well stroke patients respond to clot-busting or clot-removal treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.