Monitoring and managing vaginal health using advanced imaging technology

Continuous Monitoring and Management of Vaginal Health via Multifunctional OCT/OCTA Endoscopy

NIH-funded research University of California-Irvine · NIH-10297772

This study is looking to make treatments for Genitourinary Syndrome of Menopause better for women by using a new imaging system that helps doctors see what's happening in the vagina during laser therapy, so they can tailor the treatment to each woman's needs and improve their overall care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10297772 on NIH RePORTER

What this research studies

This research focuses on improving the treatment of Genitourinary Syndrome of Menopause (GSM), which affects many women and impacts their quality of life. It aims to develop a new endoscopic imaging system that combines Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) to provide real-time insights into vaginal health during laser treatments. By using this technology, the research seeks to identify which patients would benefit most from laser therapy, optimize treatment parameters, and enhance follow-up care, all while minimizing the need for invasive procedures. This approach could lead to more personalized and effective management of GSM symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are women experiencing symptoms of Genitourinary Syndrome of Menopause who are unable or unwilling to undergo hormone therapy.

Not a fit: Patients who do not have symptoms of GSM or those who are already receiving effective treatment for their condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide women suffering from GSM with safer and more effective treatment options that do not rely on hormone therapy.

How similar studies have performed: Previous research in dermatology has shown success with laser micro-ablation techniques, suggesting potential for similar advancements in female pelvic medicine.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.