Monitoring and guiding the growth of cancer cell subtypes
Engineering model-based systems to monitor and steer subclonal dynamics
['FUNDING_R21'] · H. LEE MOFFITT CANCER CTR & RES INST · NIH-10833036
This study is creating a new software tool to help scientists watch how different types of cancer cells grow and change over time, which could lead to better treatments for patients like you.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | H. LEE MOFFITT CANCER CTR & RES INST (nih funded) |
| Locations | 1 site (TAMPA, UNITED STATES) |
| Trial ID | NIH-10833036 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the complex behavior of cancer cell subtypes by developing a software tool called CLONEID. It aims to monitor how these subtypes evolve over time in laboratory settings, using advanced computer vision techniques to track their growth and changes. By linking genetic profiles with observable traits, the research seeks to provide insights into the dynamics of cancer cell populations, which could lead to improved treatment strategies. Patients may benefit from this work as it could enhance the understanding of cancer behavior and inform more effective therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with various types of cancer who may benefit from advanced monitoring of their tumor's genetic and phenotypic characteristics.
Not a fit: Patients with stable, non-evolving tumors or those not undergoing treatment may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments by providing deeper insights into tumor dynamics.
How similar studies have performed: Other research has shown promise in using computer vision and multi-omic approaches to study cancer dynamics, indicating that this methodology could be effective.
Where this research is happening
TAMPA, UNITED STATES
- H. LEE MOFFITT CANCER CTR & RES INST — TAMPA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ANDOR, NOEMI — H. LEE MOFFITT CANCER CTR & RES INST
- Study coordinator: ANDOR, NOEMI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer