Molecular signs that predict Type 2 diabetes patterns in South Asian adults
Molecular Prediction, Disease Progression, and Type 2 Diabetes (T2D) Phenotypes in South Asians
This project looks for molecular signs that predict which South Asian adults with prediabetes or early diabetes will develop different types of Type 2 diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11502743 on NIH RePORTER |
What this research studies
You would be part of research using a large, long-term group of mainly South Asian adults who have been followed for many years and have banked blood and health records. Researchers will analyze genes, metabolites, and other molecular markers to link them with specific diabetes patterns, how the disease progresses, and who develops complications. The team will combine this molecular data with clinical information from the Precision-CARRS cohort to find signals that come before worsening diabetes or death. Results may help identify people at higher risk earlier and point to tailored prevention or treatment options.
Who could benefit from this research
Good fit: Ideal candidates would be South Asian adults (age 21+) with prediabetes or early Type 2 diabetes who are part of, or eligible for, the Precision-CARRS cohort or affiliated clinics.
Not a fit: People without South Asian ancestry or those without available clinical records or banked samples are unlikely to directly benefit from this specific project.
Why it matters
Potential benefit: If successful, this work could help doctors identify South Asian patients at higher risk for specific, more dangerous forms of Type 2 diabetes earlier.
How similar studies have performed: Previous work in European populations has identified diabetes subgroups and some molecular markers, but applying these molecular predictions specifically to South Asians is relatively new and less tested.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Narayan, Kabayam M Venkat — Emory University
- Study coordinator: Narayan, Kabayam M Venkat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.