Molecular profiling and biobank for Alzheimer’s disease
Molecular Profiling (MP) Core G
Collecting and analyzing small, self‑collected blood samples from people across the country to find genetic signals linked to memory problems and Alzheimer’s.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-11184298 on NIH RePORTER |
What this research studies
This project runs a central biobank that tracks, stores, and ships blood samples and related data to other research teams. Participants provide dried blood spot cards that are genotyped for markers like APOE and array‑based variants, and the resulting data are added to the study repository. Samples are shared twice yearly with the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) so other scientists can use them. The core also reanalyzes genomic data as methods improve and advises investigators on biomarker development.
Who could benefit from this research
Good fit: Ideal candidates are adults—particularly older adults or those with memory concerns—who can enroll in the MindCrowd‑Expanded program and provide a self‑collected dried blood spot sample by mail.
Not a fit: People who cannot provide a mailed blood sample or who are not enrolled in the participating cohort are unlikely to benefit directly from this specific program.
Why it matters
Potential benefit: By pooling and sharing genetic and molecular data, this work could speed up discovery of risk markers and lead to better ways to predict or monitor Alzheimer’s.
How similar studies have performed: Large biobanks and genotyping projects (for example ADNI and other population cohorts) have successfully identified genetic risk factors like APOE, so this approach is well established and likely to yield useful data.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Huentelman, Matt — University of Arizona
- Study coordinator: Huentelman, Matt
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.