Molecular causes of cancer and ways to prevent it
Project 04: Molecular Carcinogenesis and Chemoprevention (MCC)
This program works to understand how genes, diet, and the environment lead to cancer and to develop diet or drug strategies to lower cancer risk for people at higher risk.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11263186 on NIH RePORTER |
What this research studies
At Ohio State a multidisciplinary team studies how genetic factors and exposures (like chemicals, hormones, microbes, and diet) interact over time to cause cancer. Researchers use laboratory studies, analyses of human samples and data, and translational projects to link molecular changes to real-world risk. The program also develops chemoprevention and dietary approaches and helps set standards for genetic screening and counseling. Their goal is to reduce new cancers and improve outcomes for people in Ohio and beyond.
Who could benefit from this research
Good fit: Ideal candidates are people at increased cancer risk (for example due to family history, genetic findings, or precancerous conditions) or those interested in prevention-focused programs or trials.
Not a fit: People seeking treatments for immediate advanced or rapidly progressing cancer or those with unrelated health conditions are unlikely to gain direct short-term benefit from prevention-focused work.
Why it matters
Potential benefit: If successful, this work could lead to better prevention options, clearer screening guidelines, and fewer new cancers in high-risk people.
How similar studies have performed: There have been notable prevention successes before (for example tamoxifen in breast cancer and aspirin in colorectal cancer), and this program builds on those ideas while adding modern molecular and dietary approaches.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Clinton, Steven K — Ohio State University
- Study coordinator: Clinton, Steven K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.