Modifying gut bacteria with engineered probiotics for better health
Tunable therapeutic modulation of the gut microbiome by engineered probiotics
This study is exploring new types of probiotics that can better settle in your gut and help improve your digestive health, aiming to create better treatments for gut-related issues that you might face.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10451749 on NIH RePORTER |
What this research studies
This research focuses on developing engineered probiotics that can effectively integrate into the gut microbiome to improve health outcomes. By understanding how these probiotics can colonize the gut and deliver therapeutic benefits, the research aims to create more effective treatments for gastrointestinal diseases. The approach involves identifying key factors that influence probiotic colonization and designing advanced tools to enhance their effectiveness. Patients may benefit from new therapies that target specific gut-related health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from gastrointestinal diseases or disorders who may benefit from enhanced probiotic therapies.
Not a fit: Patients with stable gastrointestinal health or those who do not have any gastrointestinal disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative probiotic therapies that significantly improve gastrointestinal health and treat related disorders.
How similar studies have performed: Previous research has shown promise in using engineered probiotics for therapeutic purposes, indicating that this approach has potential for success.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Dantas, Gautam — Washington University
- Study coordinator: Dantas, Gautam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.