Modifying antibodies to enhance their immune functions
Glycoengineering of antibodies to modulate immune functions
This study is looking at ways to make antibodies work better for treating cancer and autoimmune diseases by changing the sugar molecules on them, which could lead to new and more effective treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Maryland, College Park NIH-funded |
| Lab location | 1 site (College Park, United States) |
| Project ID | NIH-10900746 on NIH RePORTER |
What this research studies
This research focuses on improving the effectiveness of antibodies, which are crucial for treating conditions like cancer and autoimmune diseases. By using a specialized method to alter the sugar molecules attached to antibodies, the researchers aim to create more effective versions that can better engage the immune system. The study will explore how these modifications can enhance the antibodies' ability to kill cancer cells and reduce inflammation. Patients may benefit from new therapies that are more effective in treating their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with cancer or autoimmune diseases who may benefit from enhanced antibody treatments.
Not a fit: Patients who do not have cancer or autoimmune diseases are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective antibody therapies for cancer and autoimmune diseases.
How similar studies have performed: Previous research has shown promising results in modifying antibodies to improve their therapeutic effects, indicating a potential for success in this approach.
Where this research is happening
College Park, United States
- Univ of Maryland, College Park — College Park, United States (Active)
Researchers
- Principal investigator: Wang, Lai-Xi — Univ of Maryland, College Park
- Study coordinator: Wang, Lai-Xi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.