Modeling the tricuspid valve in children with heart defects
Computer Modeling of the Tricuspid Valve in Hypoplastic Left Heart Syndrome
This study is looking at how the tricuspid valve works in kids with Hypoplastic Left Heart Syndrome to help doctors create better surgery plans that fit each child's heart, aiming to improve their health and reduce complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10849738 on NIH RePORTER |
What this research studies
This research focuses on understanding the tricuspid valve in children with Hypoplastic Left Heart Syndrome (HLHS), a condition where the left side of the heart is underdeveloped. By using advanced 3D echocardiography and computer modeling, the study aims to analyze the unique structure of the tricuspid valve and its relationship to heart function and complications like tricuspid regurgitation. The goal is to develop better surgical strategies tailored to each patient's anatomy, potentially improving outcomes for those affected by this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and children diagnosed with Hypoplastic Left Heart Syndrome.
Not a fit: Patients with heart conditions other than Hypoplastic Left Heart Syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical techniques and better survival rates for children with HLHS.
How similar studies have performed: Previous research has shown promising results using 3D modeling techniques in other heart conditions, indicating potential for success in this novel application.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Jolley, Matthew — Children's Hosp of Philadelphia
- Study coordinator: Jolley, Matthew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.