Modeling the impact of social factors on chronic diseases

RFA-DP-23-001, Simulation Model of Interventions Linking Evidence to SDOH (SMILES)

NIH-funded research Research Triangle Institute · NIH-10897686

This study is looking at how things like where you live, your job, and your income can affect the chances of getting chronic diseases and how long people live, so we can find better ways to help everyone stay healthy over the next few decades.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-10897686 on NIH RePORTER

What this research studies

This research aims to create a mathematical simulation model that examines how social determinants of health (SDOH) influence the incidence and mortality of chronic diseases over the next 5 to 30 years. By integrating various risk factors and SDOH elements, the model will help identify effective programs and policies that can reduce health disparities. It will generate synthetic populations to represent diverse characteristics, allowing for tailored insights at the county and state levels. The findings could inform public health strategies and interventions to improve health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals living in communities with high rates of chronic diseases and significant social determinants impacting their health.

Not a fit: Patients with acute conditions or those not affected by chronic diseases may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that significantly reduce chronic disease rates and health disparities in communities.

How similar studies have performed: Other research has shown success in using simulation models to address public health issues, indicating that this approach has potential for impactful outcomes.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.