Modeling how tumors grow and metabolize in their environment
Spatio-temporal mechanistic modeling of whole-cell tumor metabolism
['FUNDING_R21'] · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · NIH-10831070
This study is looking at how tumors grow and change in their surroundings to help find better ways to treat cancer, so patients can have more effective therapies based on what we learn.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10831070 on ClinicalTrials.gov |
What this research studies
This research investigates the metabolic characteristics of tumors and their surrounding environments to better understand cancer development and treatment strategies. By utilizing advanced computational methods, the project aims to create detailed models that simulate tumor growth dynamics and metabolism in a three-dimensional context. The approach combines high-throughput data with insights from cellular biophysics to forecast how tumors behave and respond to therapies. Patients may benefit from improved therapeutic strategies derived from these insights.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancer who are seeking innovative treatment options.
Not a fit: Patients with non-malignant conditions or those not currently undergoing cancer treatment may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments by providing a deeper understanding of tumor metabolism and growth.
How similar studies have performed: While there have been successful studies using mathematical models in cancer research, the specific combination of 3D spatio-temporal dynamics with detailed metabolism modeling is relatively novel.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEGRE, DANIEL — BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
- Study coordinator: SEGRE, DANIEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer