Modeling how seasonal and pandemic influenza spreads and affects populations.

RFA-IP20-003: Individual-based Simulation of Seasonal and Pandemic Influenza Epidemics - supplement Emergency Response to the COVID-19 Pandemic

['FUNDING_U01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10907396

This study is looking at how the flu spreads and changes over time, especially during the COVID-19 pandemic, to help improve vaccines and health responses, so that everyone can have better protection and treatment against the flu.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-10907396 on ClinicalTrials.gov

What this research studies

This research focuses on creating detailed models to simulate the spread of seasonal and pandemic influenza, particularly in the context of the COVID-19 pandemic. By collaborating with multiple expert groups, the project aims to understand how influenza viruses evolve and how immunity from vaccinations changes over time. The goal is to improve public health responses and vaccination strategies by accurately predicting influenza outbreaks and their impacts on healthcare systems. Patients may benefit from insights gained through this modeling, which could lead to better prevention and treatment strategies for influenza.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit include individuals at higher risk for influenza complications, such as the elderly and those with underlying health conditions.

Not a fit: Patients who are not at risk for influenza or who have already received effective vaccinations may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccination strategies and public health responses to influenza outbreaks, ultimately reducing illness and death rates.

How similar studies have performed: Other research has shown success in using modeling approaches to predict influenza outbreaks and improve public health responses, indicating that this approach is both tested and promising.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.