Modeling how measles spreads in populations with mass vaccination
Disease Persistence and Population Dynamics: Modeling Measles under Mass Vaccination
This study looks at why measles outbreaks can still happen in communities where many people are vaccinated, and it aims to find ways to stop these outbreaks for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10656486 on NIH RePORTER |
What this research studies
This research investigates the dynamics of measles transmission in populations that have undergone mass vaccination. By using advanced mathematical and statistical modeling techniques, the study aims to identify the factors that contribute to the persistence of measles outbreaks despite high vaccination rates. It will explore various elements such as vaccination rates, demographic changes, contact patterns, and migration to understand how these factors influence disease spread. The findings could help in developing targeted interventions to prevent future outbreaks.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include children under 11 years old, particularly those in areas with fluctuating vaccination rates.
Not a fit: Patients who are already fully vaccinated against measles and live in regions with stable vaccination coverage may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for measles prevention and control, ultimately protecting vulnerable populations.
How similar studies have performed: Previous research has shown success in using mathematical modeling to understand infectious disease dynamics, indicating that this approach is both valid and potentially impactful.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Yang, Wan — Columbia University Health Sciences
- Study coordinator: Yang, Wan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.