Modeling how inflammation affects tissue mechanics

Computational Biomechanics Modeling of Inflammation

['FUNDING_OTHER'] · UNIVERSITY OF NOTRE DAME · NIH-10896364

This study is looking at how inflammation affects the way our body tissues behave, using computer models to help us understand these changes better, which could lead to better ways to diagnose and treat related health issues for patients like you.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF NOTRE DAME (nih funded)
Locations1 site (NOTRE DAME, UNITED STATES)
Trial IDNIH-10896364 on ClinicalTrials.gov

What this research studies

This research investigates the physical laws that govern the behavior of living tissues, particularly focusing on inflammation and swelling. By developing advanced computational models, the team aims to understand how inflammation alters tissue mechanics and cellular behavior over time and space. This approach combines mechanics, computation, and biology to provide insights into the underlying processes of various diseases. Patients may benefit from improved diagnostic and treatment strategies based on these findings.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing inflammatory conditions affecting various tissues.

Not a fit: Patients with non-inflammatory conditions or those not affected by tissue swelling may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic tools and treatment options for diseases associated with inflammation.

How similar studies have performed: Other research has shown promise in using computational models to understand tissue mechanics, indicating that this approach could yield valuable insights.

Where this research is happening

NOTRE DAME, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.