Modeling how complex microbial communities affect children's health
Statistical and agent-based modeling of complex microbial systems: a means for..
This study is looking at how germs from poop can affect the health of kids living in low-income neighborhoods in Kenya, especially those who drink cow's milk and have to deal with dirty living conditions, to find better ways to keep them safe from infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project ID | NIH-10857133 on NIH RePORTER |
What this research studies
This research investigates the impact of complex microbial communities, particularly those transmitted through feces, on the health of children in low-income urban areas of Kenya. By using statistical and agent-based modeling, the study aims to understand how societal development influences the transmission of enteric infections among children, especially those exposed to cow's milk and living in environments with poor sanitation. The researchers will analyze data from various households to identify patterns in pathogen transmission and develop effective intervention strategies to reduce infection rates. This approach combines computational methods with real-world data to address a significant public health issue.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years living in low-income urban neighborhoods, particularly those exposed to enteric pathogens.
Not a fit: Patients who do not live in high-burden areas or those who are not within the specified age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing enteric infections in children, ultimately reducing morbidity and mortality rates.
How similar studies have performed: Previous research has shown success in understanding microbial communities and their impact on health, suggesting that this approach could yield valuable insights.
Where this research is happening
Iowa City, United States
- University of Iowa — Iowa City, United States (Active)
Researchers
- Principal investigator: Sewell, Daniel — University of Iowa
- Study coordinator: Sewell, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.