Modeling how cells function and interact
Mechanistic Modeling of Cellular Systems
['FUNDING_OTHER'] · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · NIH-10928706
This study is working on new computer tools to help scientists better understand how cells work, which could lead to better treatments for diseases like cancer and heart problems, ultimately helping patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT (nih funded) |
| Locations | 1 site (FARMINGTON, UNITED STATES) |
| Trial ID | NIH-10928706 on ClinicalTrials.gov |
What this research studies
This research aims to create a national resource that provides advanced computational tools for modeling cellular systems. It utilizes software platforms like COPASI and Virtual Cell (VCell) to simulate various biophysical mechanisms that control cell functions, such as reaction kinetics and membrane transport. Patients can benefit from this research as it enhances our understanding of cellular processes, which can lead to improved treatments for diseases like cancer and cardiovascular conditions. The project will support a large community of cell and systems biologists, ultimately translating complex cellular interactions into actionable insights for patient care.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with cancers or cardiovascular diseases, as the findings may enhance treatment strategies for these conditions.
Not a fit: Patients with conditions unrelated to cellular function or those not requiring advanced modeling techniques may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating diseases by improving how we model and predict cellular behavior.
How similar studies have performed: Previous research utilizing computational modeling tools like VCell and COPASI has shown success in advancing our understanding of cellular mechanisms, indicating that this approach is both tested and promising.
Where this research is happening
FARMINGTON, UNITED STATES
- UNIVERSITY OF CONNECTICUT SCH OF MED/DNT — FARMINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LOEW, LESLIE M — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
- Study coordinator: LOEW, LESLIE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers