Modeling Hepatitis D Infection and Treatment Response
Data-Driven Mathematical and Computational Modeling of Hepatitis D Infection and Treatment Response
This study is looking at how the hepatitis delta virus (HDV) works alongside the hepatitis B virus (HBV) in people who have both infections, to find better treatments that can help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Loyola University Chicago NIH-funded |
| Lab location | 1 site (Maywood, United States) |
| Project ID | NIH-10771934 on NIH RePORTER |
What this research studies
This research investigates the dynamics of hepatitis delta virus (HDV) infection and treatment response in patients co-infected with hepatitis B virus (HBV). It employs a combination of clinical trials, experimental studies in humanized mouse models, and advanced mathematical and computational modeling to better understand how HDV interacts with HBV and the host's immune response. The goal is to characterize the effectiveness of new antiviral therapies and improve treatment outcomes for patients suffering from chronic HDV infection.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are chronically infected with hepatitis D and hepatitis B viruses.
Not a fit: Patients who do not have hepatitis D or hepatitis B infections may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and potentially effective therapies for patients with chronic hepatitis D infection.
How similar studies have performed: Other research has shown promise in understanding viral dynamics and treatment responses in similar viral infections, indicating that this approach could yield valuable insights.
Where this research is happening
Maywood, United States
- Loyola University Chicago — Maywood, United States (Active)
Researchers
- Principal investigator: Dahari, Harel — Loyola University Chicago
- Study coordinator: Dahari, Harel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.