Modeling brain tumors to predict treatment outcomes
Multi-scale modeling of glioma for the prediction of treatment response, treatment monitoring and treatment allocation
This study is working on new computer models that combine different types of patient information to help doctors better understand how people with aggressive brain tumors, like gliomas, will respond to treatments, aiming to improve care and outcomes for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11079529 on NIH RePORTER |
What this research studies
This research focuses on developing advanced computational models that integrate various types of patient data, including imaging and molecular profiles, to better predict how patients with aggressive brain tumors, specifically gliomas, will respond to treatments. By utilizing informatics algorithms, the project aims to enhance the accuracy of treatment monitoring and allocation, potentially allowing for earlier detection of treatment responses and disease progression. The goal is to create a framework that provides actionable insights for clinicians, improving patient care and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with IDH wild-type high-grade gliomas who are undergoing treatment.
Not a fit: Patients with other types of brain tumors or those not currently receiving treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with gliomas.
How similar studies have performed: Previous research in multi-scale modeling has shown promise in predicting clinical outcomes, suggesting that this approach could yield significant advancements in treatment strategies.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Gevaert, Olivier — Stanford University
- Study coordinator: Gevaert, Olivier
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.