Modeling blood clotting risk in patients with atrial fibrillation
Multiscale Modeling of Clotting Risk in Atrial Fibrillation
This study is working on new ways to understand how blood flows and clots in the hearts of people with atrial fibrillation, so doctors can give more personalized treatment and help reduce the risk of blood clots just for you.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10458660 on NIH RePORTER |
What this research studies
This research aims to create advanced models that simulate how blood flows and clots in the heart of patients with atrial fibrillation (AF). By integrating various scientific principles, the project seeks to understand the unique anatomical features of each patient's heart, which can influence their risk of developing blood clots. The goal is to provide personalized assessments of clotting risk, moving away from one-size-fits-all approaches that may lead to unnecessary treatments. This could ultimately help doctors make better decisions regarding anticoagulation therapy for AF patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with atrial fibrillation who are at risk for blood clots and stroke.
Not a fit: Patients with atrial fibrillation who do not have any risk factors for blood clots or those who are not eligible for anticoagulation therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized treatment plans for patients with atrial fibrillation, reducing unnecessary anticoagulation therapy.
How similar studies have performed: Other research has shown promise in using advanced modeling techniques to assess clotting risks, indicating that this approach could be effective.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Griffith, Boyce Eugene — Univ of North Carolina Chapel Hill
- Study coordinator: Griffith, Boyce Eugene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.