Modeling Alzheimer's Disease related dementias in marmosets
Modeling Alzheimer's Disease Related Dementias in the Marmoset
['FUNDING_OTHER'] · SALK INSTITUTE FOR BIOLOGICAL STUDIES · NIH-10705182
This study is looking at marmosets to learn more about the early stages of Alzheimer's and other types of dementia, so we can find better ways to diagnose and treat these conditions for people who are affected.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SALK INSTITUTE FOR BIOLOGICAL STUDIES (nih funded) |
| Locations | 1 site (La Jolla, UNITED STATES) |
| Trial ID | NIH-10705182 on ClinicalTrials.gov |
What this research studies
This research aims to create models of Alzheimer's Disease related dementias (ADRD) using marmosets, which are longer-living mammals. By studying these models, researchers hope to understand the early stages of ADRD, which can last many years before symptoms appear. The project will investigate various forms of dementia, including frontotemporal degeneration and Lewy body dementia, to identify potential therapeutic targets and improve diagnostic tools. This approach seeks to bridge the gap between basic neuroscience and clinical applications, ultimately benefiting human patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for Alzheimer's Disease or those showing early signs of dementia.
Not a fit: Patients with advanced dementia or those not at risk for Alzheimer's Disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for Alzheimer's Disease and related dementias.
How similar studies have performed: Previous research using animal models has shown promise in understanding dementia, but this approach with marmosets is relatively novel.
Where this research is happening
La Jolla, UNITED STATES
- SALK INSTITUTE FOR BIOLOGICAL STUDIES — La Jolla, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, KUO-FEN — SALK INSTITUTE FOR BIOLOGICAL STUDIES
- Study coordinator: LEE, KUO-FEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease, Gehrig's Disease, Lou Gehrig Disease