NIH-funded research NIH-funded research

Mobile phone support to help young adults in Zambia manage HIV and reduce substance use

Official title: Adapting mHealth interventions to improve self-management of HIV and substance use among emerging adults in Zambia

Funded at Univ of Massachusetts Med Sch Worcester · NIH-11134651 · Data updated 2026-11-12

This project will adapt a four‑session counseling program into mobile sessions and add motivational text messages to help 18–24-year-olds in Zambia living with HIV stay on treatment and cut down on alcohol or drug use.

More Substance Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Massachusetts Med Sch Worcester
NIH-funded
Lab location1 site (Worcester, United States)
Project startSeptember 30, 2023
Project endJuly 31, 2026
Funding year2025
Award (this year)$158,831
NIH project number5R34DA059935-03
Project IDNIH-11134651 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are 18–24-year-olds in Zambia living with HIV who have difficulties with medication adherence or who use alcohol or other substances.

Less likely to help

People outside the 18–24 age range, those not in Zambia, individuals without reliable mobile phone access, or those needing intensive inpatient substance‑use treatment may not benefit from this mobile intervention.

What this research studies

The team will convert the in-person Healthy Choices counseling into a mobile format (mHC) and create Motivational Text Messaging (MTM) delivered through a computerized platform. They will use a Multiphase Optimization Strategy (MOST) to test which components or combinations work best for young people. The work includes development, cultural adaptation, and a pilot test with emerging adults living with HIV in Zambia. If I join, I could receive mobile counseling sessions and regular motivating texts focused on medication adherence, clinic attendance, and reducing substance use.

Why it matters

Potential benefit: If successful, this could make it easier for young adults with HIV in Zambia to maintain medication adherence, stay engaged in care, and reduce harmful substance use through convenient phone-based support.

How similar studies have gone: In-person Healthy Choices programs and other mobile/text-message adherence interventions have shown promising results, though combining and adapting these approaches for Zambian emerging adults is relatively new.

Where this research is happening

  • Univ of Massachusetts Med Sch Worcester
    Worcester, United States
    Active

Researchers

  • Principal investigator: Wang, Bo — Univ of Massachusetts Med Sch Worcester
  • Study coordinator: Wang, Bo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.