NIH-funded research NIH-funded research

Mobile app to help prevent suicide in teens

Official title: An Efficacy Trial of Mobile Technology for Reducing and Preventing Adolescent Suicide

Funded at Oui Therapeutics, INC · NIH-11078341 · Data updated 2026-11-12

A smartphone-based therapy app designed to reduce suicidal thoughts and behaviors in teenagers.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOui Therapeutics, INC
NIH-funded
Lab location1 site (New Haven, United States)
Project startFebruary 15, 2021
Project endMarch 31, 2027
Funding year2025
Award (this year)$596,110
NIH project number5R42MH125691-04
Project IDNIH-11078341 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents who have recent suicidal thoughts or behaviors and can use a smartphone for app-based therapy.

Less likely to help

Those without access to a smartphone, who need immediate inpatient care, or who prefer non-digital therapies may not benefit from this app-based approach.

What this research studies

If you join, you would use a smartphone app that delivers therapeutic tools aimed at lowering suicidal thoughts and self-harm. Teen participants will be randomly assigned to receive the enhanced app or a comparison condition and will complete regular questionnaires and safety checks. The research team will monitor responses and reach out if there are signs of immediate risk. The study tests whether this mobile approach can lower suicide-related thoughts and behaviors over time.

Why it matters

Potential benefit: If successful, this could give teens an accessible on-phone tool to help reduce suicidal thoughts and attempts.

How similar studies have gone: Some digital cognitive-behavioral and suicide-prevention apps have shown promise, but rigorous randomized trials are still limited and this builds on a phase I beta version.

Where this research is happening

  • Oui Therapeutics, INC
    New Haven, United States
    Active

Researchers

  • Principal investigator: Simon, Patricia — Oui Therapeutics, INC
  • Study coordinator: Simon, Patricia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.