Mixed-metal effects on children's brain health in rural Bangladesh

Building Capacity to study mixed metal-induced neurotoxicity in rural Bangladeshi children-A1

NIH-funded research Sam Houston State University · NIH-11121047

This project trains local scientists to look at how exposure to metals like arsenic, lead, manganese, and cadmium may harm thinking and development in children living in rural Bangladesh.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSam Houston State University NIH-funded
Lab location1 site (Huntsville, United States)
Project IDNIH-11121047 on NIH RePORTER

What this research studies

U.S. and Bangladeshi researchers are working together to measure children's exposure to several toxic metals and to carry out simple tests of thinking, behavior, and development. Local teams will be trained in collecting samples, laboratory analysis of metals, neurobehavioral testing, and data analysis so they can run and interpret future studies. The project focuses on mixed-metal exposure because children are often exposed to more than one metal at a time, and it will develop methods to link combined exposures with child outcomes. Over time, the effort aims to build a local research network capable of monitoring and addressing metal-related threats to children's brain health.

Who could benefit from this research

Good fit: Children living in rural Bangladeshi communities with possible exposure to arsenic, lead, manganese, or cadmium, and their families willing to take part in exposure testing and child development assessments.

Not a fit: Children outside the affected rural regions, adults without relevant metal exposures, or anyone unable to take part in local testing may not directly benefit from this specific project.

Why it matters

Potential benefit: If successful, this work could help detect and prevent metal-related harm to children's brain development and guide local public health actions.

How similar studies have performed: Previous studies in Bangladesh have linked single-metal exposures to subtle neurobehavioral problems in children, but studies addressing combined exposures and building local research capacity are less common.

Where this research is happening

Huntsville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.