NIH-funded research R01 grant

MIO: Helping mothers in recovery boost parenting and child well‑being

Official title: A Type I Hybrid Effectiveness-Implementation Trial of "Mothering from the Inside Out" (MIO)

Funded at Baystate Medical Center, INC. · NIH-11396965 · Data updated 2026-11-12

A program called Mothering from the Inside Out helps mothers in substance use recovery improve their parenting and their children’s security.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBaystate Medical Center, INC.
NIH-funded
Lab location1 site (Springfield, United States)
Project startSeptember 30, 2024
Project endJuly 31, 2029
Funding year2026
Award (this year)$700,049
NIH project number5R01DA058125-03
Project IDNIH-11396965 on NIH RePORTER

Who could benefit from this research

Could help

Mothers with substance use disorders and their young children who are in outpatient treatment settings.

Less likely to help

Families not engaged in outpatient SUD treatment or mothers without reflective functioning needs may see limited benefit.

What this research studies

This project tests how well an attachment-based parenting approach works for mothers with substance use disorders. It focuses on improving parental reflective functioning so mothers can better understand and regulate their own emotions and respond to their children’s needs. The study builds on prior trials and explores how different implementation conditions affect outcomes in real-world treatment settings. By understanding what helps or hinders MIO in community clinics, it aims to close the gap between research and practice. The ultimate goal is safer, more nurturing relationships for mothers and their children who are navigating recovery together.

Why it matters

Potential benefit: If successful, families could experience stronger parenting, less maternal distress, and fewer relapses, improving children’s attachment and behavior.

How similar studies have gone: Prior trials showed benefits when delivered by researchers, with mixed results when delivered by community counselors, informing this implementation focus.

Where this research is happening

  • Baystate Medical Center, INC.
    Springfield, United States
    Active

Researchers

  • Principal investigator: Peacock-Chambers, Elizabeth — Baystate Medical Center, INC.
  • Study coordinator: Peacock-Chambers, Elizabeth

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.