Mindfulness plus AI to personalize care for chronic low back pain

IMPACT: Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment

['FUNDING_OTHER'] · WORCESTER POLYTECHNIC INSTITUTE · NIH-10992095

Using AI and wearable and survey data to find which adults with chronic low back pain are likely to benefit from a mindfulness-based program.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWORCESTER POLYTECHNIC INSTITUTE (nih funded)
Locations1 site (WORCESTER, UNITED STATES)
Trial IDNIH-10992095 on ClinicalTrials.gov

What this research studies

You would join a program that delivers Mindfulness-Based Stress Reduction (MBSR) for chronic low back pain while researchers collect sleep, activity, heart rate variability, mood, pain, and social support data over time. The team will start with a smaller group (about 50 people) and then expand to a larger sample (target nā‰ˆ350) to build and test machine learning models that predict who improves with MBSR. Data will come from wearable monitors, questionnaires, and clinical visits to track changes during and after the program. The goal is to use those measurements to guide future choices about non-drug pain care.

Who could benefit from this research

Good fit: Adults (21+) with chronic low back pain who can attend MBSR sessions, use wearable monitors, and complete questionnaires are the ideal candidates.

Not a fit: People without chronic low back pain, those unable to participate in MBSR classes or wear monitoring devices, or those with conditions that prevent safe participation may not benefit from this work.

Why it matters

Potential benefit: If successful, the project could help match people with chronic low back pain to mindfulness therapy that is most likely to help them and avoid treatments that won't.

How similar studies have performed: Mindfulness programs have helped some people with chronic back pain, but using AI on wearables and biopsychosocial data to predict individual response is a newer and still emerging approach.

Where this research is happening

WORCESTER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.