Mindfulness Apps for Teen Anxiety and Depression

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

NIH-funded research Mclean Hospital · NIH-11101339

This project explores how smartphone mindfulness apps help teenagers manage anxiety and depression and who benefits most from using them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMclean Hospital NIH-funded
Lab location1 site (Belmont, United States)
Project IDNIH-11101339 on NIH RePORTER

What this research studies

Many teenagers use mindfulness apps like Headspace to cope with feelings of anxiety and sadness. This project aims to understand how these apps work in the brain and for which teens they are most effective. Participants, aged 13-18, will use either a mindfulness app or a different active control app. Before and after using the app, they will have brain scans (fMRI) to see how their brain activity changes. This will help us learn more about the mental processes involved in feeling better.

Who could benefit from this research

Good fit: Ideal candidates are adolescents aged 13-18 who experience symptoms of anxiety or depression and are interested in using a smartphone app to help manage these feelings.

Not a fit: Patients who do not experience anxiety or depressive symptoms, or who are not interested in app-based interventions, may not find direct benefit from this particular research.

Why it matters

Potential benefit: If successful, this work could lead to better recommendations for which teenagers might benefit most from mindfulness apps, offering a convenient and accessible way to support their mental well-being.

How similar studies have performed: While mindfulness meditation has shown promise for anxiety and depression, there is limited research specifically on how app-based mindfulness works for teenagers.

Where this research is happening

Belmont, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.