Mindfulness and self-hypnosis to ease chronic pain in older adults

Mechanisms of Mindfulness Meditation and Self-Hypnosis for Pain in Older Adults with Chronic Pain

NIH-funded research University of Washington · NIH-11197593

This project compares mindfulness meditation and self-hypnosis to help reduce chronic pain in people aged 60 and older.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11197593 on NIH RePORTER

What this research studies

You would be invited to learn mindfulness meditation or self-hypnosis through a structured program and attend sessions over several weeks. The study uses safe experimental pain tests and brain imaging (fMRI) plus EEG to measure how your nervous system and brain respond before and after the training. Researchers will compare changes in your pain reports and brain signals to understand how each technique changes pain processing. The team will also look at patient characteristics that might predict who benefits most from each approach.

Who could benefit from this research

Good fit: Adults aged 60 years or older who have ongoing chronic pain and can attend in-person visits at the study site are ideal candidates.

Not a fit: People with only short-term (acute) pain, major cognitive impairment, or medical implants/conditions that prevent MRI may not benefit or qualify for participation.

Why it matters

Potential benefit: If successful, these mind-body approaches could reduce chronic pain and help decrease reliance on opioid medications for older adults.

How similar studies have performed: Prior studies have shown mindfulness and self-hypnosis can lower pain and change brain activity, but their specific effects and mechanisms in older adults are not yet fully established.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.