MIND diet plus aerobic exercise for Black adults with high blood pressure to lower dementia risk
MIND Foods and Aerobic Training in Black Adults with HTN: An ADRD Prevention Pilot RCT (MAT)
['FUNDING_R01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-11311336
A program offering the MIND eating plan and regular aerobic exercise to Black adults with high blood pressure to help lower the chance of memory loss and dementia.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-11311336 on ClinicalTrials.gov |
What this research studies
This pilot randomized program was co-designed with safety-net clinics and Black patients to combine hypertension self-management, the MIND diet, and aerobic training tailored to community preferences. Participants will attend blood-pressure education classes, get practical guidance and supports for following the MIND diet, and take part in structured aerobic activity that can be done at home or locally. The focus is on making the changes sustainable and acceptable in real-world safety-net care settings. Study staff will track blood pressure, fitness, and thinking/memory over time to see how the combined approach works.
Who could benefit from this research
Good fit: Black (non-Hispanic) adults aged 21 and older with hypertension who are willing to try diet changes and aerobic activity are ideal candidates.
Not a fit: People without high blood pressure, those under age 21, or those who cannot safely participate in aerobic exercise or dietary changes may not benefit from this program.
Why it matters
Potential benefit: If successful, the program could lower blood pressure and improve brain health, reducing future risk of Alzheimer's and related dementias among Black adults.
How similar studies have performed: Prior studies suggest MIND-style diets and aerobic exercise can help heart health and slow cognitive decline, but combining them and co-designing the approach for Black adults with hypertension is relatively new and being tested here.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CLARK, DANIEL O — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: CLARK, DANIEL O
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.