NIH-funded research R01 grant

Milk Type in Toddlers: How Whole or Low-Fat Milk Affects Child Health

Official title: Milk Type in Toddlers (Milk-TOT) Study: Impact of Whole versus Low-fat Milk on Child Adiposity, Health and Development

Funded at Univ of Calif/div/agriculture/nat/resour · NIH-11141719 · Data updated 2026-11-12

This project wants to learn if whole milk or low-fat milk is better for toddlers' weight, health, and development between ages 2 and 3.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of Calif/div/agriculture/nat/resour
NIH-funded
Lab location1 site (Oakland, United States)
Project startSeptember 15, 2023
Project endJune 30, 2028
Funding year2025
Award (this year)$687,187
NIH project number5R01DK131217-03
Project IDNIH-11141719 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are parents of toddlers who are 2 years old and have successfully transitioned from breastmilk or formula to cow's milk.

Less likely to help

Toddlers outside the 2-3 year age range or those not consuming cow's milk may not directly benefit from participating in this specific project.

What this research studies

Current recommendations suggest toddlers switch from whole milk to low-fat milk at age two, but there isn't much strong evidence to support this. In fact, some observations suggest low-fat milk might be linked to more body fat in children. This project will recruit 625 parents of toddlers and randomly assign them to give their child either whole milk or 1% milk for one year. We will then compare how these milk types affect changes in body fat and overall body mass.

Why it matters

Potential benefit: If successful, this could provide clear guidance for parents and healthcare providers on the optimal milk fat type for toddlers to support healthy growth and prevent obesity.

How similar studies have gone: Existing observational studies have shown conflicting results, and there are surprisingly few rigorous trials to support current recommendations, making this a novel and important investigation.

Where this research is happening

  • Univ of Calif/div/agriculture/nat/resour
    Oakland, United States
    Active

Researchers

  • Principal investigator: Ritchie, Lorrene D — Univ of Calif/div/agriculture/nat/resour
  • Study coordinator: Ritchie, Lorrene D

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.