NIH-funded research NIH-funded research

Military HIV Clinical Trials Unit

Official title: The Military HIV Research Program (MHRP) Clinical Trial Unit

Funded at Henry M. Jackson Fdn for the Adv Mil/med · NIH-11459070 · Data updated 2026-11-12

This program runs clinical trials of new HIV vaccines, prevention approaches, and TB treatments for adults at risk of or living with HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHenry M. Jackson Fdn for the Adv Mil/med
NIH-funded
Lab location1 site (Bethesda, United States)
Project startDecember 10, 2013
Project endNovember 30, 2027
Funding year2026
Award (this year)$555,378
NIH project number3UM1AI108568-13S1
Project IDNIH-11459070 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 21 and older who are living with HIV, at high risk for HIV, or who live in regions with substantial HIV/TB burden are the typical candidates for these trials.

Less likely to help

Children under 21, people who do not meet specific trial eligibility, or those with medical exclusions would not be eligible and likely would not benefit from participation.

What this research studies

This program expands a network of clinics managed by Walter Reed and the Henry M. Jackson Foundation to run HIV and TB clinical trials. The network includes a coordinating core in Maryland and eight international clinical research sites in Africa and Asia that will host phase I through phase III trials. Sites will partner with groups like HVTN, HPTN, ACTG, and IAVI to test vaccines, prevention tools, and treatment strategies. If I live near one of these sites, I could be invited to join a specific trial depending on the study's purpose and eligibility rules.

Why it matters

Potential benefit: If successful, the program could bring new HIV vaccines, better prevention options, and improved TB treatments to people in high‑burden regions.

How similar studies have gone: There are proven prevention tools like PrEP and effective antiretroviral treatments, but HIV vaccines and combined HIV/TB interventions remain experimental, so this network builds on prior advances while testing new approaches.

Where this research is happening

  • Henry M. Jackson Fdn for the Adv Mil/med
    Bethesda, United States
    Active

Researchers

  • Principal investigator: Robb, Merlin L — Henry M. Jackson Fdn for the Adv Mil/med
  • Study coordinator: Robb, Merlin L

Related research

Other NIH-funded projects on the same topics.

  • Cooperation partners of SETBP1 in AML development

    This grant explores how SETBP1 and AF9 (MLLT3) work together to drive acute myeloid leukemia and whether targeting related epigenetic regulators could help treat aggressive CK-AML.

    NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-11625528

  • U.S. Military HIV Research Program Clinical Trials Unit expansion

    A nationwide network of clinical trial sites is being expanded to test HIV prevention and treatment approaches through DAIDS-supported trials.

    NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-11609389

  • Novel protein biomarkers of chronic pain in adults using a pain registry biobank

    A study in adults with chronic pain will look for new protein biomarkers in blood samples to understand better why pain persists and how to improve treatment.

    NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-11498721

  • Tailored antibody cures for HIV using AI and vaccines

    A study to design personalized antibody-based strategies to achieve HIV remission, using lab experiments and computer models to tailor vaccines or antibody treatments to individuals or small groups.

    NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-11483233

  • Understanding how antibody protection works using 3D protein structures

    Researchers will build a 3D-based method to see which viral features relate to prevention by antibodies, using data from people in HIV vaccine and monoclonal antibody trials.

    NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-11470978

  • Military HIV Clinical Network

    This program runs HIV and TB prevention and treatment clinical studies for adults in military-associated and high-HIV-burden communities.

    NIH research Henry M. Jackson Fdn for the Adv Mil/med · Bethesda, United States · NIH-11459071

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.