Mid-America emergency-care clinical trials center

Renewal of The Mid-America CTSA Consortium (MACC) as a Regional Clinical Center for SIREN

NIH-funded research University of Chicago · NIH-11251802

This project continues and expands a regional emergency-care trials center that connects adults to clinical studies of emergency treatments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11251802 on NIH RePORTER

What this research studies

You may be asked about studies when you come to an emergency department in the Mid‑America network, because this center helps run and enroll patients in emergency-care trials. The renewal moves the coordinating hub to the University of Chicago, funds local research coordinators at six sites, and adds a Patient Accrual Liaison to find and enroll eligible patients more quickly. MACC already has a strong track record of enrolling and retaining patients in SIREN trials. The goal is to make it easier for adult patients to join relevant emergency-care research when they need urgent treatment.

Who could benefit from this research

Good fit: Adults treated at participating hospitals who meet each trial's eligibility rules could be invited to join studies supported by this center.

Not a fit: People not treated at participating hospitals or who do not have the emergency conditions being studied would likely not benefit directly from this project.

Why it matters

Potential benefit: If successful, it could give more adults faster access to new emergency treatments by enrolling more people into trials.

How similar studies have performed: This builds on prior SIREN trials and MACC's strong past enrollment and retention records, so the approach is grounded in proven experience.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.