Microneedles delivering pain relief for osteoarthritis
Single-administration microneedles with controlled sustained release of non-opioid analgesics to treat osteoarthritis pain
This study is exploring a new way to deliver pain relief for osteoarthritis using tiny microneedles, which could help you manage your pain with fewer injections and less stomach upset.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Storrs NIH-funded |
| Lab location | 1 site (Storrs-Mansfield, United States) |
| Project ID | NIH-10618335 on NIH RePORTER |
What this research studies
This research investigates a novel method of delivering non-opioid analgesics through microneedles to treat pain associated with osteoarthritis. The approach aims to provide a single administration that allows for controlled and sustained release of pain medication, potentially reducing the need for frequent injections or high oral doses. By using microneedles, the research seeks to improve the absorption of analgesics while minimizing systemic side effects commonly associated with traditional pain management methods. Patients may experience less gastrointestinal issues and improved compliance due to the convenience of this delivery method.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with osteoarthritis who experience chronic joint pain.
Not a fit: Patients who do not have osteoarthritis or those who are allergic to the specific analgesics being tested may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective pain management option for patients suffering from osteoarthritis.
How similar studies have performed: Previous research has shown promise in using microneedle technology for drug delivery, indicating potential success for this novel approach.
Where this research is happening
Storrs-Mansfield, United States
- University of Connecticut Storrs — Storrs-Mansfield, United States (Active)
Researchers
- Principal investigator: Nguyen, Thanh — University of Connecticut Storrs
- Study coordinator: Nguyen, Thanh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.