Michigan emergency and critical care network

Michigan SIREN Collaborative

NIH-funded research Wayne State University · NIH-11284053

This program links hospitals and EMS teams so people with sudden, serious emergencies can be enrolled in coordinated emergency care and clinical trials more quickly.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWayne State University NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-11284053 on NIH RePORTER

What this research studies

From a patient view, this network brings together major hospitals and universities across Michigan (and partner sites) so emergency patients can be enrolled in clinical work aimed at improving care. It uses a hub-and-spoke setup with designated STEMI, trauma, burn, and children’s centers and close coordination with EMS. The network uses streamlined, three-tiered enrollment procedures, shared staff roles, and prior experience with Exception From Informed Consent (EFIC) to reduce errors and increase timely enrollment. That structure helps sites run high-quality emergency research and give diverse patients access to new emergency treatments.

Who could benefit from this research

Good fit: People treated for acute, life-threatening problems (for example severe trauma, heart attack, major burns, pediatric emergencies, or urgent neurologic events) at participating hospitals are the most likely candidates.

Not a fit: People with routine or non-urgent outpatient conditions or those cared for outside the participating hospital network are unlikely to benefit directly from this program.

Why it matters

Potential benefit: If successful, this could speed delivery of better emergency treatments and expand access to cutting-edge care for critically ill patients.

How similar studies have performed: This network builds on prior successful emergency research hubs and has been a top enroller in the SIREN network and other EFIC studies.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.