Michigan Alzheimer's Clinical Program

Core B: Clinical Core

NIH-funded research University of Michigan at Ann Arbor · NIH-11129863

This program follows people at risk for or showing early signs of Alzheimer's and collects medical tests, brain scans, and samples to help future treatments.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11129863 on NIH RePORTER

What this research studies

You would be followed over time as part of a long-term group where clinicians collect medical exams, memory tests, brain scans, and blood or other samples. The program is expanding from about 414 to 550 participants and focuses on people at risk for or showing the earliest signs of cognitive decline. It includes a Detroit site with substantial Black American participation and plans outreach to Hispanic/Latino communities in Grand Rapids. Data, images, and biological samples are shared with national repositories to support many clinical trials and observational studies.

Who could benefit from this research

Good fit: Ideal candidates are older adults at risk for or experiencing early memory problems, including individuals from Black and Hispanic/Latino communities targeted by the program.

Not a fit: People without cognitive concerns or those with advanced dementia who cannot attend regular follow-up visits are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could help researchers find new causes of brain decline and speed development of better tests and treatments for people with Alzheimer's disease.

How similar studies have performed: Large long-term cohorts (for example ADNI) have helped identify useful biomarkers, so the cohort approach is proven, though the emphasis on non-amyloid contributors is comparatively newer.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.