Metabolic Markers in Brain Chemistry with AI-Enhanced MRS
Official title: TRD 2: Metabolic Markers
Funded at Hugo W. Moser Res Inst Kennedy Krieger · NIH-11334985 · Data updated 2026-11-12
A brain-imaging project aims to develop AI-driven MRI techniques to measure brain chemistry in healthy people and those with disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hugo W. Moser Res Inst Kennedy Krieger NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $164,590 |
| NIH project number | 2P41EB031771-06 |
| Project ID | NIH-11334985 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who can undergo brain MRI, including those with and without brain conditions, in research settings.
✕Less likely to help
People unable to undergo MRI or participate in scans, such as those with MRI contraindications, may not benefit.
What this research studies
This project will create advanced magnetic resonance spectroscopy methods to map brain chemistry, using AI to adapt acquisitions in real time for higher data quality. It focuses on making MRS and ST-MRI acquisitions more robust to movement and instrument fluctuations, improving workflow efficiency. The team will develop processing and analysis tools to quantify brain metabolites and establish quality metrics that help ensure reliable results across studies.
Why it matters
Potential benefit: If successful, patients could benefit from more accurate brain chemical measurements that support better diagnosis and tracking of brain disorders.
How similar studies have gone: Previous work shows AI-enhanced MRS can improve data quality, but this project emphasizes robust methods for wide clinical use.
Where this research is happening
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Hugo W. Moser Res Inst Kennedy Krieger
Baltimore, United States Active
Researchers
- Principal investigator: Edden, Richard Anthony Edward — Hugo W. Moser Res Inst Kennedy Krieger
- Study coordinator: Edden, Richard Anthony Edward
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.