Metabolic Basis of Disease: Building Talent and Tools to Understand Metabolism in illness
Official title: Metabolic Basis of Disease - Phase 2
Funded at Lsu Pennington Biomedical Research Ctr · NIH-11378724 · Data updated 2026-11-12
A NIH P20 grant supports growing researchers and upgrading infrastructure to study how metabolism affects diseases like heart failure, liver cancer, and undernutrition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Pennington Biomedical Research Ctr NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project start | March 1, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $2,197,409 |
| NIH project number | 5P20GM135002-07 |
| Project ID | NIH-11378724 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with heart failure with preserved ejection fraction, hepatocellular carcinoma, or metabolic complications of undernutrition.
✕Less likely to help
Some patients without these specific metabolic disease contexts may not directly benefit.
What this research studies
This grant aims to develop young scientists and strengthen the resources needed to explore how metabolic processes influence various diseases. It funds three research leaders with complementary projects on heart failure with preserved ejection fraction, hepatocellular carcinoma, and iron metabolism in undernutrition. APreclinical and molecular mechanism cores will provide mentoring, technical support, and enhanced bioinformatics capacity to accelerate discoveries. The program emphasizes bioinformatics and new leadership to translate metabolic insights into human health benefits.
Why it matters
Potential benefit: If successful, this program could lead to better understanding of metabolic triggers in disease and faster development of targeted therapies.
How similar studies have gone: Phase 1 COBRE efforts established core infrastructures and mentoring; Phase 2 aims to expand and accelerate progress.
Where this research is happening
-
Lsu Pennington Biomedical Research Ctr
Baton Rouge, United States Active
Researchers
- Principal investigator: Stephens, Jacqueline M — Lsu Pennington Biomedical Research Ctr
- Study coordinator: Stephens, Jacqueline M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.