Memory and thinking problems after a stroke
Post-stroke Cognitive Impairment and Dementia
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11184400
This project uses hospital and Medicare records to find how often people get memory and thinking problems after a stroke and what raises their risk.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11184400 on ClinicalTrials.gov |
What this research studies
If I had a stroke, this project would pull together my hospital record and Medicare data along with millions of other stroke records to build a real-world database about post-stroke memory and thinking problems. Researchers will link two million stroke records from over 2,000 U.S. hospitals with claims data to measure how common post-stroke cognitive impairment and dementia are and which risk factors are involved. They will examine cardiovascular conditions and common medications (such as blood pressure medicines, antithrombotics, and statins) to see how these relate to later thinking problems. The effort will create a resource to help clinicians spot high-risk patients and inform strategies to prevent cognitive decline after stroke.
Who could benefit from this research
Good fit: People who have had a recent or prior stroke and are represented in hospital registries or Medicare records would be the focus of this work.
Not a fit: People without a history of stroke or without hospital/Medicare records are unlikely to be directly affected by this project.
Why it matters
Potential benefit: If successful, this work could help doctors identify stroke survivors at high risk for dementia and shape treatments or prevention strategies to reduce that risk.
How similar studies have performed: Large registry and claims studies have improved understanding of stroke outcomes, but large-scale, focused work specifically on post-stroke dementia is limited and still emerging.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XIAN, YING — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: XIAN, YING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease