Memory and brain aging in Latino adults

Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's disease

NIH-funded research University of California, San Diego · NIH-11285241

This project looks at how heart health, genes, brain scans, and life experiences affect memory and Alzheimer’s risk in Latino adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11285241 on NIH RePORTER

What this research studies

You would join a long-term, diverse Latino group where researchers collect 10 years of cognitive tests, brain MRIs, and advanced blood markers related to Alzheimer's. They will also perform detailed heart-health exams, genetic testing (including APOE), and questionnaires about social and cultural factors. The team will combine these measures to find early signs and risk patterns that might explain higher dementia rates in Latino communities. Participation may involve clinic visits, imaging, blood or saliva samples, and follow-up testing over time.

Who could benefit from this research

Good fit: Ideal candidates are Latino adults (age 21 and older), especially middle-aged and older people, willing to undergo cognitive testing, MRIs, heart-health exams, and give blood or saliva for genetic and biomarker testing.

Not a fit: People who are not Latino, who cannot undergo MRI or blood draws, or who already have advanced dementia and cannot participate in tests may not benefit directly from this study.

Why it matters

Potential benefit: If successful, this work could identify earlier detection methods and prevention targets tailored to Latino communities.

How similar studies have performed: Prior research links cardiovascular health and genetics to dementia risk, but long-term, deeply phenotyped biomarker studies focused specifically on diverse Latino groups are rare.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.