Melanoma tissue and bioinformatics support center
Pathology and Bioinformatics Core
This project builds tissue banks, biomarker tests, and computer-based analyses to improve diagnosis and treatment options for people with melanoma.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11184363 on NIH RePORTER |
What this research studies
Researchers collect and store tumor and biopsy samples and link them with detailed clinical information. They run lab-based biomarker tests and use genomic and transcriptomic computer analyses to map how melanoma tumors interact with the immune system. The team develops new methods to measure multiple markers in tissue sections and integrates data across projects and species to create a comprehensive picture. Experts also provide quality control, biobanking, and statistical and bioinformatics support to other studies in the program.
Who could benefit from this research
Good fit: Ideal participants are people with melanoma who can donate tumor or biopsy samples and share their clinical information for research.
Not a fit: People without melanoma, those unable to provide tissue samples, or those seeking immediate treatment benefits are unlikely to benefit directly from this core.
Why it matters
Potential benefit: Could lead to better biomarkers and more personalized immunotherapy approaches for melanoma patients.
How similar studies have performed: Tissue banking combined with bioinformatics has previously identified biomarkers that guide melanoma immunotherapy, while the project's advanced spatial tissue analyses are a newer but promising approach.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Rodig, Scott J — Massachusetts General Hospital
- Study coordinator: Rodig, Scott J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.