MedSupport: Helping families overcome barriers to kids' chemotherapy medicines

MedSupport: A Novel Multilevel Intervention to Identify and Address Barriers to Pediatric Medication

NIH-funded research Roswell Park Cancer Institute Corp · NIH-11508243

This program offers extra support to parents of children with acute lymphoblastic leukemia to help them give home chemotherapy medicines more reliably.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRoswell Park Cancer Institute Corp NIH-funded
Lab location1 site (Buffalo, United States)
Project IDNIH-11508243 on NIH RePORTER

What this research studies

If your family joins, you will be randomly assigned to receive the MedSupport program or standard education, and the study will follow about 150 families across eight pediatric cancer centers. MedSupport is a multilevel, theory-based program designed to identify the specific reasons medicines are missed and provide tailored help to address them. The study uses electronic medication monitoring caps and blood or other metabolite tests to measure how often medicines are actually taken. The trial runs alongside a therapeutic pediatric cancer trial and compares adherence and the proposed mechanisms between the groups.

Who could benefit from this research

Good fit: Ideal candidates are families of children (roughly birth to 11 years) with acute lymphoblastic leukemia who are taking home-based chemotherapy and are willing to use electronic monitoring and provide biospecimens.

Not a fit: Children who are not on home-based chemotherapy, have a different cancer type, or families unwilling to use monitoring devices or give samples are unlikely to benefit from this program.

Why it matters

Potential benefit: If effective, MedSupport could help families reduce missed chemo doses and lower the chance of treatment complications or relapse for children with ALL.

How similar studies have performed: Previous research shows medication nonadherence is common and supportive interventions can help, but combining electronic monitoring with drug-metabolite biomarkers in this pediatric ALL setting is relatively new.

Where this research is happening

Buffalo, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer Relapse
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.