MedSupport: helping families manage children's chemotherapy medications

MedSupport: A Novel Multilevel Intervention to Identify and Address Barriers to Pediatric Medication

NIH-funded research Roswell Park Cancer Institute Corp · NIH-11309614

MedSupport is a support program to help families of children with acute lymphoblastic leukemia follow home chemotherapy schedules and reduce missed doses.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRoswell Park Cancer Institute Corp NIH-funded
Lab location1 site (Buffalo, United States)
Project IDNIH-11309614 on NIH RePORTER

What this research studies

If your child has ALL and receives chemotherapy at home, you would be asked to join a program that combines practical help, education, and tools to tackle common medication barriers. Families are randomly assigned to receive the MedSupport program or usual education, and the team will follow medication use over time at eight pediatric cancer centers. Medication use will be tracked with electronic pill-bottle caps and by measuring drug metabolites to see how well doses are taken. The study also looks at why the program works by testing theory-based mechanisms that link the support to better adherence.

Who could benefit from this research

Good fit: Families of children (infants through about 11 years old) with acute lymphoblastic leukemia who are receiving portions of their chemotherapy at home are the ideal candidates.

Not a fit: Children who are not receiving home-based chemotherapy, who have other types of cancer, or whose caregivers cannot participate in follow-up visits are unlikely to benefit directly from this program.

Why it matters

Potential benefit: If successful, this program could help families keep children on their chemotherapy schedule more reliably and lower the chance of relapse or hospitalization.

How similar studies have performed: Medication-adherence supports and electronic monitoring have shown promise in other pediatric conditions, but combining multilevel behavioral support with drug-metabolite biomarkers in pediatric ALL is relatively new.

Where this research is happening

Buffalo, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer Relapse
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.