Mechanistic insights into modern catalytic reactions for safer, smarter chemical synthesis
Official title: Mechanistic Investigation into Modern Catalytic Reactions
Funded at State University of Ny,binghamton · NIH-11382964 · Data updated 2026-11-12
This grant explores how new catalytic reactions work, especially using light-driven chemistry and engineered enzymes, to help scientists design better, safer ways to make pharmaceuticals and other valuable chemicals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of Ny,binghamton NIH-funded |
| Lab location | 1 site (Binghamton, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $386,800 |
| NIH project number | 5R35GM147183-05 |
| Project ID | NIH-11382964 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patients directly; this is fundamental chemistry research.
✕Less likely to help
No direct patient benefit in the short term.
What this research studies
If this project succeeds, you may see clearer, more reliable explanations of how cutting-edge catalytic methods operate. Researchers will study how light-activated catalysts and engineered P450 enzymes drive bond-making steps, using innovative probes to map transition states. The work aims to calibrate theoretical models with real-world measurements so future chemists can predict outcomes more accurately. While this is basic science, the findings could streamline the development of new drugs and materials. Participation would come in the form of laboratory-based collaboration and potential future applications in related projects.
Why it matters
Potential benefit: Better understanding of catalytic reactions could accelerate the development of safer, more efficient drug and chemical manufacturing.
How similar studies have gone: Previous studies have successfully linked experimental probes to mechanism in photoredox and biocatalytic systems, supporting this approach.
Where this research is happening
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State University of Ny,binghamton
Binghamton, United States Active
Researchers
- Principal investigator: Hirschi, Jennifer — State University of Ny,binghamton
- Study coordinator: Hirschi, Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.